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Can R-407C Be Used to Replace R-22?
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Can R-407C Be Used to Replace R-22?

Can R-407C Be Used to Replace R-22?

June 19, 2025

 

With the phase-out of R-22, many HVAC professionals are considering alternatives for retrofitting existing systems. One of the most common replacements is R-407C. But can it truly replace R-22? Here's what you need to know.

 

1. Yes — But Only in Retrofit Applications

R-407C is a viable drop-in replacement for R-22 in existing systems, but only with proper modifications. It is not suitable for use in R-22 systems without adjustments.

*System must be retrofitted — including oil change to POE and component checks.

 

2. Similar Performance

Cooling capacity and efficiency of R-407C are close to R-22.

Works at similar pressures, making it easier to adapt in older systems.

However, R-407C is a zeotropic blend, so fractionation may occur if the system leaks and is not recharged properly.

 

3. Oil Compatibility

R-22 systems use mineral oil.

R-407C requires POE oil.

You must flush and replace the lubricant when converting.

 

4. Lower Environmental Impact

R-407C has zero ozone depletion potential (ODP).

GWP (~1,774) is still significant but lower than many alternatives.

 

5. Widely Available and Cost-Effective

R-407C is a mature, proven alternative — easy to source and affordable, making it a popular choice for light commercial and residential retrofits.

 

R-407C can replace R-22 in existing systems with proper retrofitting. It offers a balance of performance, availability, and compliance, making it a smart choice for HVAC professionals serving aging equipment.

 

Need help sourcing R-407C or planning a retrofit? Contact our team for B2B pricing and technical support.

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