Can R-407C Be Used to Replace R-22?
Jun 19, 2025
With the phase-out of R-22, many HVAC professionals are considering alternatives for retrofitting existing systems. One of the most common replacements is R-407C. But can it truly replace R-22? Here's what you need to know.
1. Yes — But Only in Retrofit Applications
R-407C is a viable drop-in replacement for R-22 in existing systems, but only with proper modifications. It is not suitable for use in R-22 systems without adjustments.
*System must be retrofitted — including oil change to POE and component checks.
2. Similar Performance
Cooling capacity and efficiency of R-407C are close to R-22.
Works at similar pressures, making it easier to adapt in older systems.
However, R-407C is a zeotropic blend, so fractionation may occur if the system leaks and is not recharged properly.
3. Oil Compatibility
R-22 systems use mineral oil.
R-407C requires POE oil.
You must flush and replace the lubricant when converting.
4. Lower Environmental Impact
R-407C has zero ozone depletion potential (ODP).
GWP (~1,774) is still significant but lower than many alternatives.
5. Widely Available and Cost-Effective
R-407C is a mature, proven alternative — easy to source and affordable, making it a popular choice for light commercial and residential retrofits.
R-407C can replace R-22 in existing systems with proper retrofitting. It offers a balance of performance, availability, and compliance, making it a smart choice for HVAC professionals serving aging equipment.
Need help sourcing R-407C or planning a retrofit? Contact our team for B2B pricing and technical support.
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